1887

Abstract

SUMMARY

Infection with herpes simplex viruses type 1 or 2 prevented the aggregation of 7-day-old chick heart cells into smooth, spheroidal, spontaneously beating aggregates. Virus infection also caused a loosening of peripheral cells in aggregates formed from initially uninfected cells. Measurements of rate of attachment of labelled single heart cells to a monolayer of like cells (homotypic), to HEp-2 cells (heterotypic), or to plastic substrata (nonspecific adhesion) indicated that virus infection caused a significant but differential loss of homotypic and nonspecific adhesiveness, but no alteration in heterotypic attachment rates. These observations indicate that those cell surface changes induced by viruses which are related to cell adhesion can be quantified by techniques measuring attachment rates.

Loading

Article metrics loading...

/content/journal/jgv/10.1099/0022-1317-38-3-437
1978-03-01
2024-05-02
Loading full text...

Full text loading...

/deliver/fulltext/jgv/38/3/JV0380030437.html?itemId=/content/journal/jgv/10.1099/0022-1317-38-3-437&mimeType=html&fmt=ahah

References

  1. Abercrombie M. 1976; The contact behavior of invading cells. In Cellular Membranes and Tumor Cell Behavior pp 21–37 Baltimore: Williams and Wilkins;
    [Google Scholar]
  2. Balsamo J., Lilien J. 1974; Functional identification of three components which mediate tissue-type specific embryonic adhesion. Nature, London 251:522–524
    [Google Scholar]
  3. Barbera A. J. 1976; Adhesive recognition between developing retinal cells and the optic tecta of the chick embryo. Developmental Biology 46167–191
    [Google Scholar]
  4. Batra G. K., Nahmias A. J., Dehaan R. L. 1976; Herpes simplex virus stops spontaneous beating of chick heart cells. Nature, London 259:677–679
    [Google Scholar]
  5. Buck C. A., Glick M. C., Warren L. 1971; Glycopeptides from the surface of control and virus-transformed cells. Science 172:169–171
    [Google Scholar]
  6. Cassiman J. J., Bernfield M. R. 1976; Use of preformed cell aggregates and layers to measure tissue-specific differences in intercellular adhesion. Developmental Biology 62:231–245
    [Google Scholar]
  7. Culp L. A. 1974; Substrate-attached glycoproteins mediating adhesion of normal and virus-transformed mouse fibroblasts. Journal of Cell Biology 63:71–83
    [Google Scholar]
  8. Darlington R. W., Granoff A. 1973; Replication-biological aspects. In The Herpesviruses pp 93–132 Edited by Kaplan A. S. New York: Academic Press;
    [Google Scholar]
  9. Dehaan R. L. 1970; The potassium-sensitivity of isolated embryonic heart cells increases with development. Developmental Biology 23:226–240
    [Google Scholar]
  10. Dorsey J. K., Roth S. 1973; Adhesive specificity in normal and transformed mouse fibroblasts. Developmental Biology 33:249–256
    [Google Scholar]
  11. Ejercito P. M., Kieff D., Roizman B. 1968; Characterization of herpes simplex virus strains differing in their effect on social behaviour of infected cells. Journal of General Virology 3:357–364
    [Google Scholar]
  12. Fritz M. D., Nahmias A. J. 1972; Reversed polarity in transmembrane potentials of cells infected with herpesviruses. Proceedings of the Society for Experimental Biology and Medicine 139:1159–1161
    [Google Scholar]
  13. Gershman H., Drumm J., Culp L. C. 1976; Sorting out of normal and virus-transformed cells in cellular aggregates. Journal of Cell Biology 68:276–286
    [Google Scholar]
  14. Heine J. W., Spear P. G., Roizman B. 1972; The proteins specified by herpes simplex virus. VI. Viral proteins in the plasma membrane. Journal of Virology 9:431–439
    [Google Scholar]
  15. Honess R. W., Roizman B. F. 1975; Proteins specified by herpes simplex virus. XIII. Glycosylation of viral polypeptides. Journal of Virology 16:1308–1326
    [Google Scholar]
  16. Hynes R. O. 1973; Alteration of cell-surface proteins by viral transformation and by proteolysis. Proceedings of the National Academy of Sciences of the United States of America 70:3170–3174
    [Google Scholar]
  17. McClay D. R., Baker S. R. 1975; A kinetic study of embryonic cell adhesion. Developmental Biology 43:109–122
    [Google Scholar]
  18. McGuire E. J., Burdick C. L. 1976; Intercellular adhesive selectivity. I. An improved assay for the measurement of embryonic chick intercellular adhesion (liver and other tissues). Journalof Cell Biology 68:80–89
    [Google Scholar]
  19. Moore E. G. 1976; Cell to substratum adhesion-promoting activity released by normal and virus-transformed cells in culture. Journal of Cell Biology 70:634–647
    [Google Scholar]
  20. Morris J. E. 1976; Cell aggregation rate versus aggregate size. Developmental Biology 54:288–296
    [Google Scholar]
  21. Moscona A. A. 1956; Development of heterotypic combinations of dissociated embryonic chick cells. Proceedings of the Society for Experimental Biology and Medicine 92:410–416
    [Google Scholar]
  22. Moscona A. A. 1974; Surface specification of embryonic cells: lectin receptors, cell recognition and specific cell ligands. In The Cell Surface in Development pp 67–99 Edited by Moscona A. A. New York: John Wiley and Sons;
    [Google Scholar]
  23. Moyer W. A., Steinberg M. S. 1976; Do rates of intercellular adhesion measure the cell affinities reflected in cell-sorting and tissue-spreading configurations?. Developmental Biology 52:246–262
    [Google Scholar]
  24. Nahmias A. J., Del Buono I., Schneweis K., Gordon D., Thies D. 1971; Type specific surface antigens of cells infected with herpes simplex virus type 1 and 2. Proceedings of the Society for Experimental Biology and Medicine 138:21–27
    [Google Scholar]
  25. Nahmias A. J., Dowdle W. R. 1968; Antigenic and biologic differences in Herpesvirus hominis. In Progress in Medical Virology vol 10 pp 110–159 Edited by Melnick J. L. New York: K. Sarger;
    [Google Scholar]
  26. Nahmias A., Fritz M., Chang G. 1972; Herpesviruses as infectious and oncogenic agents in man and other vertebrates. In Membranes and Virus in Immunopathology pp 293–318 New York: Academic Press;
    [Google Scholar]
  27. Nahmias A., Shore S., Del Buono I. 1974; Diagnosis by immunofluorescence of human viral infections with emphasis on herpes simplex viruses. In ViralImmunodiagnosis pp 157–172 Edited by Kurstak E., Morisset R. New York: Academic Press;
    [Google Scholar]
  28. Onodera K., Sheinin R. 1970; Macromolecular glucosamine-containing component of the surface of cultivated mouse cells. Journal of Cell Sciences 7:337–355
    [Google Scholar]
  29. Orr C. W., Roseman S. 1969; Intercellular adhesion. I. A quantitative assay for measuring the rate of adhesion. Journal of Membrane Biology 1:109–124
    [Google Scholar]
  30. Poste G. 1970; Virus-induced polykaryocytosis and the mechanism of cell fusion. Advances in Virus Research 16:303–356
    [Google Scholar]
  31. Roizman B. 1962; Polykaryocytosis induced by viruses. Proceedings of the National Academy of Sciences of the United States of America 48:228–234
    [Google Scholar]
  32. Roizman B., Furlong D. 1974; The replication of herpesviruses. In Comprehensive Virology vol 4 pp 229–403 Edited by FraenkelConrat H., Wagner R. R. New York: Plenum Press;
    [Google Scholar]
  33. Roseman S. 1974; Complex carbohydrates and intercellular adhesion. In Cell Surface in Development pp 255–271 Edited by Moscona A. A. New York: John Wiley & Sons;
    [Google Scholar]
  34. Roth S., Weston J. A. 1967; The measurement of intercellular adhesion. Proceedings of the National Academy of Sciences of the United States of America 58:974–980
    [Google Scholar]
  35. Sachs H. G., Dehaan R. L. 1973; Embryonic myocardial cell aggregates: volume and pulsation rate. Developmental Biology 30:233–240
    [Google Scholar]
  36. Sheinin R. 1975; The cell surface, virus modification, and virus transformation. In Viruses, Evolution and Cancer pp 371–400 Edited by Kurstak E., Maramorosch K. New York: Academic Press;
    [Google Scholar]
  37. Shore S. L., Black C. M., Melewicz F. M., Wood P. A., Nahmias A. J. 1976; Antibody-dependent cell-mediated cytotoxicity to target cells infected with type 1 and type 2 herpes simplex virus. Journal of Immunology 116:194–201
    [Google Scholar]
  38. Spear P. G., Keller J. M., Roizman B. 1970; Proteins specified by herpes simplex virus. II. Viral glycoproteins associated with cellular membranes. Journal of Virology 5:123–131
    [Google Scholar]
  39. Steinberg M. S. 1975; Adhesion-guided multicellular assembly. Journal of Theoretical Biology 55:431–443
    [Google Scholar]
  40. Steinberg M. S., Armstrong P. B., Granger R. E. 1973; On the recovery of adhesiveness by trypsin-dissociated cells. Journal of Membrane Biology 13:97–128
    [Google Scholar]
  41. Tevethia S. S., Lowry S., Rawls W. E., Melnick J. L., McMillan V. 1972; Detection of early cell surface changes in herpes simplex virus infected cells by agglutination with concanavalin A. Journal of General Virology 5:93–97
    [Google Scholar]
  42. Walther B. B., Ohman R., Roseman S. 1973; A quantitative assay for intercellular adhesion. Proceedings of the National Academy of Sciences of the United States of America 70:1569–1573
    [Google Scholar]
  43. Weiss L. 1961; Studies on cellular adhesion in tissue culture. IV. Alteration of substrata by cell surfaces. Experimental Cell Research 25:504–517
    [Google Scholar]
  44. Weiss L. 1967 In The Cell Periphery, Metastasis, and Other Contact Phemonema New York: John Wiley & Sons, Inc;
    [Google Scholar]
  45. Weiss L., Kapes D. L. 1966; Observations on cell adhesion and separation following enzyme treatment. Experimental Cell Research 41:601–608
    [Google Scholar]
http://instance.metastore.ingenta.com/content/journal/jgv/10.1099/0022-1317-38-3-437
Loading
/content/journal/jgv/10.1099/0022-1317-38-3-437
Loading

Data & Media loading...

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error