1887

Abstract

Summary

A virus closely related to duck hepatitis B virus (DHBV) was isolated from serum and liver samples of wild migratory ducks (mallards) caught in two separate wildlife reserve parks in France. In the first one (Dombes region) 12% of wild mallards were positive for DHBV, and in the second (River Somme) 3% of mallards were found positive. The DHBV isolated from the serum of wild mallards was also associated with an endogenous DNA polymerase activity capable of completing a partially double-stranded viral DNA into a fully double-stranded DNA of 3 kb. The various replicative DNA forms reported for DHBV were also detected in the liver of wild viraemic mallards. The DNA restriction enzyme pattern of the wild mallard strain differed from that of American and French strains of DHBV. The wild mallard strain DHBV was experimentally transmitted to mallard and Pekin ducklings and induced a chronic viraemia in both varieties of infected birds. This strain might be the common ancestor of all DHBV strains isolated from domestic ducks world-wide. The discovery of a DHBV-related virus in the natural wild population might be an important clue in the study of the different roles of environmental, host and viral factors in the pathogenesis of DHBV infection, and their possible oncogenic action in ducks.

Loading

Article metrics loading...

/content/journal/jgv/10.1099/0022-1317-67-3-537
1986-03-01
2024-05-02
Loading full text...

Full text loading...

/deliver/fulltext/jgv/67/3/JV0670030537.html?itemId=/content/journal/jgv/10.1099/0022-1317-67-3-537&mimeType=html&fmt=ahah

References

  1. Alexander D. J. 1980; Avian paramyxoviruses. Veterinary Bulletin 50:737–752
    [Google Scholar]
  2. Charnay P., Pourcel C., Louise A., Fritsch A. E., Tiollais P. 1979; Cloning in Escherichia coli and physical structure of hepatitis B virion DNA. Proceedings of the National Academy of Sciences, U.S.A. 76:2222–2226
    [Google Scholar]
  3. Cova L., Hantz O., Arliaud-Gassin M., Chevalier A., Berthillon P., Boulay J., Jacquet C., Chomel B., Vitvitski L., Trepo C. 1985; Comparative study of DHBV DNA levels and endogenous DNA polymerase activity in naturally infected ducklings in France. Journal of Virological Methods 10:251–260
    [Google Scholar]
  4. Cummings I. W., Browne J. K., Saiser W. A., Tyler R. L., Snyder J. M., Smolec J. M., Summers J. 1980; Isolation, characterization and comparison of recombinant DNAs derived from the human hepatitis B and woodchuck hepatitis virus genome. Proceedings of the National Academy of Sciences, U.S.A 77:1842–1846
    [Google Scholar]
  5. Delacour J. 1973; Domestic mallards. In The Waterfowl of the World vol. 4 pp. 161–166 Feltham: Hamlyn Publishing Group;
    [Google Scholar]
  6. Galibert F., Chen T. N., Mandart E. 1981; Localization and nucleotide sequence of the gene coding for the woodchuck hepatitis virus surface antigen: comparison with the gene coding for the human hepatitis B virus surface antigen. Proceedings of the National Academy of Sciences, U.S.A. 78:5315–5319
    [Google Scholar]
  7. Halpern M., England J. M., Deery D. T., Petco D. J., Mason W. S., Molnar-Kimber K. L. 1983; Viral nucleic acid synthesis and antigen accumulation in pancreas and kidney of Pekin ducks infected with duck hepatitis B virus. Proceedings of the National Academy of Sciences, U.S.A 80:4865–4869
    [Google Scholar]
  8. Hannoun C., Devaux J. M. 1980; Circulation of influenza viruses in the bay of the Somme river. Comparative Immunology, Microbiology and Infectious Diseases 3:177–183
    [Google Scholar]
  9. Hantz O., Allaudeen H. S., Ooka T., De Clercq E., Trepo C. 1984; Inhibition of human and woodchuck hepatitis virus DNA polymerase by the triphosphates of acyclovir, l-(2ʹ-deoxy-2ʹ -fluoro-β-d-arabinofuranosyl)-5-iodocytosine and E-5-(2-bromoviny)-2ʹ-deoxyuridine. Antiviral Research 4:187–199
    [Google Scholar]
  10. Hinshaw V. S., Webster R. G., Turner B. 1979; Water-borne transmission of influenza A viruses?. Intervirology 11:66068
    [Google Scholar]
  11. Hinshaw V. S., Bean W. J., Webster R. G., Sriram G. 1980; Genetic reassortment of influenza viruses in the intestinal tract of ducks. Virology 102:412–419
    [Google Scholar]
  12. Kessler N., Aymard M., Calvet A. 1979; Study of a new strain of paramyxoviruses isolated from wild ducks: antigenic and biological properties. Journal of General Virology 43:273–282
    [Google Scholar]
  13. Mandart E., Kay A., Galibert F. 1984; Nucleotide sequence of a cloned duck hepatitis B virus genome: comparison with the woodchuck and human hepatitis B virus sequences. Journal of Virology 49:782–792
    [Google Scholar]
  14. Maniatis T., Fritsch E. F., Sambrook J. 1982 Molecular Cloning: A Laboratory Manual New York: Cold Spring Harbor Laboratory;
    [Google Scholar]
  15. Marion P. L., Knight S. S., Ho B. K., Guo Y. U., Robinson W. S., Popper H. 1984; Liver disease associated with duck hepatitis B virus infection of domestic ducks. Proceedings of the National Academy of Sciences, U.S.A 81:898–902
    [Google Scholar]
  16. Mason W. S., Seal G., Summers J. 1980; Virus of Pekin ducks with structural and biological relatedness to human hepatitis B virus. Journal of Virology 36:829–836
    [Google Scholar]
  17. Mason W. S., Taylor J. M., Seal G., Summers J. 1981; An HBV-like virus of domestic ducks. In Viral Hepatitis 1981 International Symposium pp. 107–116 Edited by Szmuness W., Alter H., Maynard J. Philadelphia: Franklin Institute Press;
    [Google Scholar]
  18. Mason W. S., Aldrich G., Summers J., Taylor J. M. 1982; Asymmetric replication of duck hepatitis B virus in liver cells: free minus strand DNA. Proceedings of the National Academy of Sciences, U.S.A 79:3997–4001
    [Google Scholar]
  19. Mason W. S., Halpern M. S., England J. M., Seal G., Egan J., Coates L., Aldrich C., Summers J. 1983; Experimental transmission of duck hepatitis B virus. Virology 131:375–384
    [Google Scholar]
  20. Nerome K., Ishida M., Oya A., Bosshard S. 1983; Genomic analysis of antigenically related avian paramyxoviruses. Journal of General Virology 64:465–470
    [Google Scholar]
  21. O’Connell A., Urban K. M., London W. T. 1983; Naturally occurring infection of Pekin duck embryos by duck hepatitis B virus. Proceedings of the National Academy of Sciences, U.S.A 80:1703–1706
    [Google Scholar]
  22. Omata M., Uchiumi K., Ito Y., Yokosuka O., Mori J., Terao K., WeiFa Y., O’connell A., London W. T., Okuda K. 1983; Duck hepatitis B virus and liver diseases. Gastroenterology 85:260–267
    [Google Scholar]
  23. Omata M., Yokosu O., Imazeki F., Matsuyama Y., Uchiumi K., Ito Y., Mori J., Okuda K. 1984; Transmission of duck hepatitis B virus from Chinese carrier ducks to Japanese ducklings: a study of viral DNA in serum and tissue. Hepatology 4:603–607
    [Google Scholar]
  24. Rigby P. W. J., Dieckmann M., Rhodes C., Berg P. 1977; Labellingdeoxyribonucleic acid to high specific activity in vitro by nick translation with DNA polymerase I. Journal of Molecular Biology 113:237–251
    [Google Scholar]
  25. Robinson W. S., Marion P. L., Feitelson M., Siddiqui A. 1981; The hepadna virus group: hepatitis B and related viruses. In Viral Hepatitis: 1981 International Symposium pp. 57–68 Edited by Szmuness W., Alter H., Maynard J. Philadelphia: Franklin Institute Press;
    [Google Scholar]
  26. Shafritz D. A., Rogler C. E. 1984; Molecular characterization of viral forms observed in persistent hepatitis infections, chronic liver disease and hepatocellular carcinoma in woodchucks and humans. In Viral Hepatitis and Liver Disease pp. 225–241 Edited by Vyas G. N., Dienstag J. L., Hoofnagle S. H. Orlando: Grune & Stratton;
    [Google Scholar]
  27. Snyder R. L., Summers J. 1980; Woodchuck hepatitis virus and hepatocellular carcinoma. In Viruses in Naturally Occurring Cancers pp. 447–457 Edited by Essex M., Todaro G., ZurHausen H. New York: Cold Spring Harbor Laboratory;
    [Google Scholar]
  28. Southern E. M. 1975; Detection of specific sequences among DNA fragments separated by gel electrophoresis. Journal of Molecular Biology 98:503–517
    [Google Scholar]
  29. Sprengel R., Kuhn C., Manso C., Will H. 1984; Cloned duck hepatitis B virus DNA is infectious in Pekin ducks. Journal of Virology 52:932–937
    [Google Scholar]
  30. Summers J., O’connell A., Millman J. 1975; Genome of hepatitis B virus: restriction enzyme cleavage and structure of DNA extracted from Dane particles. Proceedings of the National Academy of Sciences, U.S.A 72:4797–4801
    [Google Scholar]
  31. Tsiquaye K. N., Rapicetta M., Mccaul T., Zuckerman A. J. 1985; Experimental in ovo transmission of duck hepatitis B virus. Journal of Virological Methods 11:49–57
    [Google Scholar]
  32. Urban K. M., O’connell A. P., London T. 1985; Sequence of events in natural infection of Pekin duck embryos with duck hepatitis B virus. Journal of Virology 55:16–22
    [Google Scholar]
  33. Wahl G. M., Stern M., Stark G. R. 1979; Efficient transfer of large DNA fragments from agarose gels to diazobenzyloxymethyl-paper and rapid hybridization by using dextran sulfate. Proceedings of the National Academy of Sciences, U.S.A 76:3683–3687
    [Google Scholar]
  34. Webster R. G., Morita M., Pridgen C., Tumova B. 1976; Ortho- and paramyxoviruses from migrating feral ducks: characterization of a new group of influenza A viruses. Journal of General Virology 32:217–225
    [Google Scholar]
  35. Webster R. G., Yakhno M., Hinshaw S. V., Bean W. J., Murti G. K. 1978; Intestinal influenza: replication and characterization of influenza viruses in ducks. Virology 84:268–278
    [Google Scholar]
http://instance.metastore.ingenta.com/content/journal/jgv/10.1099/0022-1317-67-3-537
Loading
/content/journal/jgv/10.1099/0022-1317-67-3-537
Loading

Data & Media loading...

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error