f The Complete Nucleotide Sequence of the Genome of a Hepatitis B Virus Isolated from a Naturally Infected Chimpanzee
- Authors: Mark Vaudin†, Adrian J. Wolstenholme, Kwesi N. Tsiquaye, Arie J. Zuckerman, Tim J. Harrison
- J. Gen. Virol., June 1988 69: 1383-1389, doi: 10.1099/0022-1317-69-6-1383
- Subject: Animal
- Published Online:
The complete nucleotide sequence of a strain of hepatitis B virus, originally isolated from a naturally infected chimpanzee, has been determined. Interesting features of the sequence include the presence of an in-phase stop codon in the ‘pre-core’ region of the core antigen open reading frame. The sequence shows approximately 10% nucleotide divergence from all of the other hepatitis B virus sequences previously published and the possibility that this divergence is the result of passage through chimpanzees is discussed.
Present address: Plant Biotechnology Section, Imperial Chemical Industries plc, Jealott's Hill Research Station, Bracknell RG12 6EY, U.K.
© Society for General Microbiology 1988 | Published by the Microbiology Society
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