1887

Abstract

The complete nucleotide sequence of the provirus of feline foamy virus (FeFV), strain F-17, was determined, and compared to the available data for human and simian spumaviruses. In addition to the usual retroviral and genes, two open reading frames are present between the gene and the 3′-LTR, as in the simian spumaviruses, the first being the putative transactivator. The gene is predicted to encode a precursor protein of only 53 kDa compared to 70 kDa for simian spumaviruses and a doublet of 70/74 kDa for human spumavirus. The gene contains conserved splice acceptor and donor sites suggesting that, like human foamy virus, FeFV expresses its gene using a spliced mRNA.The and genes showed greater sequence similarity to their counterparts in the primate spumaviruses than the gene and additional open reading frames.

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1997-10-01
2024-05-04
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