f Host-adaptive Antigenic Variation in Bunyaviruses
- Authors: W. S. James, D. Millican
- First Published Online: 01 December 1986, Journal of General Virology 67: 2803-2806, doi: 10.1099/0022-1317-67-12-2803
- Subject: Articles
- Issue Published:
Bunyamwera virus and snowshoe hare virus (family Bunyaviridae) were passaged up to six times through mosquito cells in culture and the resultant viruses were compared to the input, mammalian cell-passed virus using monoclonal antibodies raised against the input virus. The mosquito cell-adapted virus population consisted of mutants which were better adapted to replication in the new host than was the input mammalian cell-passed virus and were differentially susceptible to neutralization by antibody.
© Society for General Microbiology 1986 | Published by the Microbiology Society
Article metrics loading...
Full text loading...
Author and Article Information
/content/journal/jgv/10.1099/0022-1317-67-12-2803dcterms_title,dcterms_subject,pub_serialTitlepub_serialIdent:journal/jgv AND -contentType:BlogPost104
/content/journal/jgv/10.1099/0022-1317-67-12-2803dcterms_title,dcterms_subject-pub_serialIdent:journal/jgv AND -contentType:BlogPost104
Figure data loading....